Cerebral aneurysms and accelerated atherosclerosis in Russell-Silver syndrome: a new subtype? Case report

J Neurosurg. 2015 Aug;123(2):467-9. doi: 10.3171/2014.11.JNS1410. Epub 2015 Jan 2.

Abstract

The authors describe the case of a 32-year-old woman known to have Russell-Silver syndrome who presented with repeated aneurysmal subarachnoid hemorrhage. Multiple intracranial aneurysms and advanced peripheral vascular disease were demonstrated. The authors postulate a link between these vascular features and the patient's genetic condition.

Keywords: LDL = low-density lipoprotein; MCA = middle cerebral artery; RSS = Russell-Silver syndrome; Russell-Silver syndrome; SAH = subarachnoid hemorrhage; aneurysm; atherosclerosis; subarachnoid hemorrhage; vascular disorders.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aneurysm, Ruptured / complications*
  • Aneurysm, Ruptured / diagnostic imaging
  • Atherosclerosis / complications*
  • Atherosclerosis / diagnostic imaging
  • Female
  • Humans
  • Intracranial Aneurysm / complications*
  • Intracranial Aneurysm / diagnostic imaging
  • Middle Cerebral Artery / diagnostic imaging*
  • Radiography
  • Silver-Russell Syndrome / complications*
  • Silver-Russell Syndrome / diagnostic imaging