Chronic lymphocytic leukemia cells in lymph nodes show frequent NOTCH1 activation

Haematologica. 2015 May;100(5):e200-3. doi: 10.3324/haematol.2014.117705. Epub 2014 Dec 31.

¹ Pathology Department, Hospital U. Marqués de Valdecilla-Santander, Spain.
² Group of Research in Lymphomas (Medical Oncology Department), Oncohematology Area, Instituto Investigación Puerta de Hierro-Majadahonda (IDIPHIM), Madrid, Spain.
³ Hematology Department, Hospital U. Puerta de Hierro-Majadahonda, Madrid, Spain.
⁴ Pathology Department, Hospital U. Gregorio Marañón, Madrid, Spain.
⁵ Cancer Epidemiology Unit, National Center for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain Cancer Epidemiology Research Group, Oncohematology Area, Instituto Investigación Puerta de Hierro-Majadahonda (IDIPHIM), Madrid, Spain.
⁶ Group of Research in Molecular Pathology of Cancer (Pathology Department), Oncohematology Area, Instituto Investigación Puerta de Hierro-Majadahonda (IDIPHIM), Madrid, Spain.
⁷ Pathology Department, Hospital U. La Paz, Madrid, Spain.
⁸ Pathology Department, Fundación Jiménez Díaz, Madrid, Spain.
⁹ Pathology Department, MD Anderson Cancer Center, Madrid, Spain.
¹⁰ Pathology Department, Hospital Virgen de la Salud, Toledo, Spain.
¹¹ Pathology Department, Hospital U. Santiago de Compostela, La Coruña, Spain.
¹² Group of Research in Lymphomas (Medical Oncology Department), Oncohematology Area, Instituto Investigación Puerta de Hierro-Majadahonda (IDIPHIM), Madrid, Spain msbeato@idiphim.org.

No abstract available

Keywords: NOTCH1 activation; chronic lymphocytic leukemia.

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