Abstract
An asymmetric formal [3 + 2]-cycloaddition between meso-aziridines and C3-alkylindoles mediated by an in situ generated magnesium catalyst was developed for asymmetric construction of pyrroloindolines. A variety of pyrroloindolines could be obtained by employing commercial available ligands with the assistance of an easily prepared achiral ligand.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aziridines / chemistry*
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Catalysis
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Indoles / chemical synthesis*
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Indoles / chemistry
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Ligands
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Magnesium / chemistry*
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Molecular Structure
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Pyrroles / chemical synthesis*
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Pyrroles / chemistry
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Stereoisomerism
Substances
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Aziridines
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Indoles
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Ligands
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Pyrroles
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hexahydropyrrolo(2,3-b)indole
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Magnesium