Diffuse Large B-Cell Lymphoma with Involvement of the Breast and Testis in a Male Patient

Eunji Choi; Jae-Cheol Jo; Dok Hyun Yoon; Shin Kim; Kyoungmin Lee; Jooryung Huh; Chan-Sik Park; Sang Wook Lee; Cheolwon Suh

doi:10.4143/crt.2013.245

Diffuse Large B-Cell Lymphoma with Involvement of the Breast and Testis in a Male Patient

Cancer Res Treat. 2015 Jul;47(3):539-43. doi: 10.4143/crt.2013.245. Epub 2014 Sep 11.

Authors

Eunji Choi¹, Jae-Cheol Jo², Dok Hyun Yoon², Shin Kim², Kyoungmin Lee², Jooryung Huh³, Chan-Sik Park³, Sang Wook Lee⁴, Cheolwon Suh²

Affiliations

¹ Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
² Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
³ Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
⁴ Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Abstract

Here we report a case of a 76-year-old man with diffuse large B-cell lymphoma (DLBCL) with simultaneous involvement of the right breast and left testicle. The patient underwent complete resection of the involved testis, followed by immunochemotherapy with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP) and prophylactic radiotherapy to the contralateral testis. Following this multimodal therapy, he achieved a complete response. This is a rare case of DLBCL involving both the breast and the testis in a male patient.

Keywords: Breast; Diffuse large B-cell lymphoma; Male; Testis.