Coming soon: probiotics-based malaria vaccines

Trends Parasitol. 2015 Jan;31(1):2-4. doi: 10.1016/j.pt.2014.11.006. Epub 2014 Dec 18.

Abstract

The beneficial health effect of gut probiotics has been known since its discovery by Élie Metchnikoff. A new study has linked the microbiome of the human gut with immunity against malaria infections. Gut probiotics represent innovative tools for malaria prevention and lead the way to novel types of vaccination strategies.

Keywords: Plasmodium falciparum; antimalarial immunity; gut microbiota; malaria; probiotics; vaccination.

Publication types

  • Comment

MeSH terms

  • Animals
  • Escherichia coli / physiology*
  • Female
  • Humans
  • Immunoglobulin M / immunology*
  • Malaria, Falciparum / immunology*
  • Malaria, Falciparum / transmission*
  • Plasmodium / physiology*
  • Polysaccharides / immunology*

Substances

  • Immunoglobulin M
  • Polysaccharides