Abstract
Reaction of porphycene isothiocyanates with primary and secondary amines leads to the formation of thiazolo[4,5-c]porphycenes, with a substantial shift in the absorption and fluorescence spectra. The conjugates show fluorescence in the near-infrared and are capable of photosensitizing the production of the cytotoxic species singlet oxygen.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amines / chemistry
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Click Chemistry*
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Fluorescence
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Infrared Rays
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Isothiocyanates / chemistry
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Molecular Structure
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Nanoparticles / chemistry*
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Porphyrins / chemical synthesis
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Porphyrins / chemistry*
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Proteins / chemistry*
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Quantum Theory
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Singlet Oxygen / chemistry
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Spectrometry, Fluorescence
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Spectrophotometry, Ultraviolet
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Theranostic Nanomedicine*
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Thiazoles / chemical synthesis
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Thiazoles / chemistry*
Substances
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Amines
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Isothiocyanates
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Porphyrins
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Proteins
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Thiazoles
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Singlet Oxygen