Microbiota talks cholera out of the gut

Amanda J Hay; Jun Zhu

doi:10.1016/j.chom.2014.10.011

Microbiota talks cholera out of the gut

Cell Host Microbe. 2014 Nov 12;16(5):549-50. doi: 10.1016/j.chom.2014.10.011. Epub 2014 Nov 12.

Authors

Amanda J Hay¹, Jun Zhu²

Affiliations

¹ Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
² Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: junzhu@upenn.edu.

PMID: 25525783
DOI: 10.1016/j.chom.2014.10.011

Abstract

In a recent Nature paper, Hsiao et al., 2014 examine microbiota contribution during and after cholera and identify commensals correlated with healing and reconstitution of the microbial community. One particular species may use intercellular communication to stymie Vibrio cholerae pathogenesis, indicating how the microbiota can restrict pathogens.

Publication types

Comment

MeSH terms

Animals
Cholera / microbiology*
Humans
Intestines / microbiology*
Male
Microbiota / physiology*
Ruminococcus / physiology*
Vibrio cholerae / pathogenicity*
Vibrio cholerae / physiology*