Concise synthesis of cyclic carbonyl compounds from haloarenes using phenyl formate as the carbonyl source

Chem Commun (Camb). 2015 Feb 4;51(10):1854-7. doi: 10.1039/c4cc09413a.

Abstract

Various cyclic carbonyl compounds were concisely synthesized by carbonylative cyclization of haloarenes bearing nucleophilic moieties under Pd catalysis. A broad substrate scope and a feasible large-scale synthesis clearly demonstrate the high applicability of the reaction as a general, user-friendly method for access to cyclic carbonyl compounds.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzene / chemistry*
  • Catalysis
  • Cyclization
  • Formates / chemistry*
  • Halogens / chemistry*
  • Ligands
  • Molecular Structure
  • Palladium / chemistry

Substances

  • Formates
  • Halogens
  • Ligands
  • Palladium
  • Benzene