[Long-term survival metastatic ovarian cancer elderly patient]

Clin Ter. 2014;165(6):305-8. doi: 10.7417/CT.2014.1774.
[Article in Italian]

Abstract

Ovarian cancer is the sixth diagnosed cancer among women worldwide, it has a high mortality and in most cases it's diagnosed in advanced stage (stage III-IV). Combination platinum-paclitaxel chemotherapy administered every 3 weeks is considered the gold standard for first-line treatment of patients with advanced ovarian cancer. Elderly patients with ovarian cancer represents a subgroup with poor prognosis because they are often treated less radically for comorbidities and age. In the present article, we report a case of a 85 year old woman who was diagnosed with stage IV ovarian carcinoma for the presence of peritoneal carcinomatosis ab initio, not radically debulked and then treated with weekly schedule platinum-based and paclitaxel. Despite not being able to complete the chemotherapy, the patient achieved excellent results and represents a case of long survival.

Keywords: Carboplatin; Elderly patient; Metastatic disease; Ovarian cancer; Paclitaxel; Peritoneal carcinosis.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Carboplatin / administration & dosage
  • Female
  • Humans
  • Neoplasms, Glandular and Epithelial / pathology*
  • Neoplasms, Glandular and Epithelial / secondary*
  • Neoplasms, Glandular and Epithelial / therapy
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / therapy
  • Paclitaxel / administration & dosage
  • Peritoneal Neoplasms / secondary*
  • Peritoneal Neoplasms / therapy

Substances

  • Carboplatin
  • Paclitaxel