A spontaneous KRT16 mutation in a dog breed: a model for human focal non-epidermolytic palmoplantar keratoderma (FNEPPK)

J Invest Dermatol. 2015 Apr;135(4):1187-1190. doi: 10.1038/jid.2014.526. Epub 2014 Dec 18.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Disease Models, Animal
  • Dogs
  • Exons
  • Female
  • Humans
  • Immunoenzyme Techniques
  • Immunohistochemistry
  • Keratin-16 / genetics*
  • Keratoderma, Palmoplantar, Diffuse / genetics*
  • Male
  • Microscopy, Fluorescence
  • Mutation*
  • Papilloma / genetics*
  • RNA, Messenger / metabolism
  • Real-Time Polymerase Chain Reaction
  • Species Specificity

Substances

  • Keratin-16
  • RNA, Messenger

Supplementary concepts

  • Hyperkeratosis of the palms and soles and esophageal papillomas