[About the impact of the dendritic cell autovaccine on the results of treatment of non-small-cell lung cancer patients]

Lik Sprava. 2013 Sep:(6):68-72.
[Article in Russian]

Abstract

In thoracic department of the National Cancer Institute studied the effectiveness of dendritic cell autovaccine in the postoperative period in non-small-cell lung cancer patients. The results, showing good tolerance dendritic cell autovaccine. Shows the formation of the expressed antigen immune response after repeated injections dendritic cell autovaccine, as manifested after 4 revaccination. Results of survival patients non-small-cell lung cancer who received postoperative dendritic cell autovaccines demonstrate the high efficiency of the method and its applicability with a minimum of side effects. Further study of survival of patients non-small-cell lung cancer who received immunotherapy treatment, monitoring of compliance with the best mode of repeated injections.

Publication types

  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Antigen Presentation
  • Antigens, Neoplasm / immunology*
  • Cancer Vaccines / administration & dosage
  • Cancer Vaccines / immunology*
  • Carcinoma, Non-Small-Cell Lung / immunology
  • Carcinoma, Non-Small-Cell Lung / mortality
  • Carcinoma, Non-Small-Cell Lung / pathology
  • Carcinoma, Non-Small-Cell Lung / therapy*
  • Cell Engineering
  • Cells, Cultured
  • Chemotherapy, Adjuvant
  • Cytotoxicity, Immunologic
  • Dendritic Cells / immunology
  • Dendritic Cells / transplantation*
  • Drug Administration Schedule
  • Female
  • Humans
  • Lung Neoplasms / immunology
  • Lung Neoplasms / mortality
  • Lung Neoplasms / pathology
  • Lung Neoplasms / therapy*
  • Male
  • Middle Aged
  • Survival Analysis
  • T-Lymphocytes, Cytotoxic / immunology
  • Vaccination

Substances

  • Antigens, Neoplasm
  • Cancer Vaccines