[Neurohumoral effect of the dopaminergic system on development of alimentary-constitutional obesity]

Lik Sprava. 2013 Sep:(6):3-10.
[Article in Ukrainian]

Abstract

Decrease in quantity and activity of dopamine receptors at patients with obesity is established. This leads to overeating, and abnormal weight gain. The article presents data on the impact of the dopaminergic system in the levels of leptin, prolactin, insulin, and the development of alimentary-constitutional obesity in these patients.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Body Mass Index
  • Dopamine / metabolism*
  • Humans
  • Hypothalamus / metabolism*
  • Hypothalamus / physiopathology
  • Insulin / metabolism
  • Leptin / metabolism
  • Neuropeptide Y / metabolism
  • Norepinephrine / metabolism
  • Obesity / metabolism*
  • Obesity / physiopathology
  • Pituitary Gland / metabolism*
  • Pituitary Gland / physiopathology
  • Prolactin / metabolism
  • Receptors, Dopamine / metabolism*
  • Synaptic Transmission*
  • Waist Circumference

Substances

  • Insulin
  • Leptin
  • Neuropeptide Y
  • Receptors, Dopamine
  • Prolactin
  • Dopamine
  • Norepinephrine