Abstract
Decrease in quantity and activity of dopamine receptors at patients with obesity is established. This leads to overeating, and abnormal weight gain. The article presents data on the impact of the dopaminergic system in the levels of leptin, prolactin, insulin, and the development of alimentary-constitutional obesity in these patients.
MeSH terms
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Body Mass Index
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Dopamine / metabolism*
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Humans
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Hypothalamus / metabolism*
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Hypothalamus / physiopathology
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Insulin / metabolism
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Leptin / metabolism
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Neuropeptide Y / metabolism
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Norepinephrine / metabolism
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Obesity / metabolism*
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Obesity / physiopathology
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Pituitary Gland / metabolism*
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Pituitary Gland / physiopathology
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Prolactin / metabolism
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Receptors, Dopamine / metabolism*
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Synaptic Transmission*
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Waist Circumference
Substances
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Insulin
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Leptin
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Neuropeptide Y
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Receptors, Dopamine
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Prolactin
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Dopamine
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Norepinephrine