Peptide-catalyzed, bioinspired silicification for single-cell encapsulation in the imidazole-buffered system

Chem Commun (Camb). 2015 Mar 28;51(25):5523-5. doi: 10.1039/c4cc08544b.

Abstract

Inspired by biosilicification of glass sponges, we designed a catalytic peptide, which formed silica structures in the imidazole-buffered solution. The peptide was adsorbed selectively onto the surface of yeast cells, and the bioinspired silicification led to the formation of a cytoprotective silica shell on individual yeast cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Buffers
  • Catalysis
  • Imidazoles / chemistry*
  • Molecular Structure
  • Particle Size
  • Peptides / chemistry*
  • Saccharomyces cerevisiae / cytology*
  • Silicon Dioxide / chemistry*
  • Single-Cell Analysis*
  • Surface Properties

Substances

  • Buffers
  • Imidazoles
  • Peptides
  • Silicon Dioxide
  • imidazole