CaCO₃ vaterite microparticles for biomedical and personal care applications

Abstract

Among the polymorph modifications of calcium carbonate, the metastable vaterite is the most practically important. Vaterite particles are applied in regenerative medicine, drug delivery and a broad range of personal care products. This manuscript scopes to review the mechanism of the calcium carbonate crystal growth highlighting the factors stabilizing the vaterite polymorph in the most cost efficient synthesis routine. The size of vaterite particles is a crucial parameter for practical applications. The options for tuning the particle size are also discussed.

Keywords: Biomineral; Calcium carbonate (CaCO(3)); Co-precipitation; Crystal growth; Vaterite polymorph.