Repetitive behavior in Rubinstein-Taybi syndrome: parallels with autism spectrum phenomenology

J Autism Dev Disord. 2015 May;45(5):1238-53. doi: 10.1007/s10803-014-2283-7.

Abstract

Syndrome specific repetitive behavior profiles have been described previously. A detailed profile is absent for Rubinstein-Taybi syndrome (RTS). The Repetitive Behaviour Questionnaire and Social Communication Questionnaire were completed for children and adults with RTS (N = 87), Fragile-X (N = 196) and Down (N = 132) syndromes, and individuals reaching cut-off for autism spectrum disorder (N = 228). Total and matched group analyses were conducted. A phenotypic profile of repetitive behavior was found in RTS. The majority of behaviors in RTS were not associated with social-communication deficits or degree of disability. Repetitive behavior should be studied at a fine-grained level. A dissociation of the triad of impairments might be evident in RTS.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child Development Disorders, Pervasive / complications
  • Child Development Disorders, Pervasive / diagnosis*
  • Child, Preschool
  • Communication Disorders / complications
  • Communication Disorders / diagnosis
  • Compulsive Behavior / complications
  • Compulsive Behavior / diagnosis*
  • Cross-Sectional Studies
  • Down Syndrome / complications
  • Down Syndrome / diagnosis*
  • Female
  • Fragile X Syndrome / complications
  • Fragile X Syndrome / diagnosis*
  • Humans
  • Male
  • Middle Aged
  • Rubinstein-Taybi Syndrome / complications
  • Rubinstein-Taybi Syndrome / diagnosis*
  • Symptom Assessment
  • Young Adult