Usefulness of screening tools in the evaluation of long-term effectiveness of DREZ lesioning in the treatment of neuropathic pain after brachial plexus injury

BMC Neurol. 2014 Dec 9:14:225. doi: 10.1186/s12883-014-0225-9.

Abstract

Background: Despite high success rate of DREZ lesioning in the treatment of intractable central pain, there is still a significant incidence of patients without satisfactory post-operative effect. The aim of the study was to evaluate the long-term effect of DREZ lesioning using both a subjective assessment using a visual analog scale (VAS) to quantify residual pain and an assessment using the screening tool (painDETECT Questionnaire, PD-Q).

Methods: DREZ lesioning was performed in 52 patients from a total 441 cases with brachial plexus injury (11.8%) during a 17-year period (1995-2011). The effect of surgery was retrospectively assessed in 48 patients.

Results: A decrease in pre-operative pain by more than 75% (Group I) was achieved in 70.8% of patients and another 20.8% reported significant improvement (Group II). The surgery was unsucessful in 8.4% (Group III). We found a significant correlation between 'improvement' groups from both methods of assessments. Patients from Group I usually complained of residual nociceptive pain according to PD-Q, patients from Group II typically had pain of unclear origin, and all cases those in Group III suffered from neuropathic pain, Cramer's V = .66, P < .001. Overall, 66.7% of patients had resolved neuropathic pain, 20.8% patients had more serious complaints and may also suffer from residual neuropathic pain, while 12.5% had unresolved neuropathic pain.

Conclusion: DREZ lesioning is a safe and effective method with success rates of about 90%. PD-Q scores correspond to subjective satisfaction with the surgery and it seems to be a suitable screening tool for finding patients with residual neuropathic pain after surgery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Brachial Plexus / injuries*
  • Electrocoagulation / methods*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neuralgia / diagnosis
  • Neuralgia / etiology
  • Neuralgia / surgery*
  • Outcome Assessment, Health Care / methods*
  • Outcome Assessment, Health Care / standards
  • Pain Measurement / methods*
  • Pain Measurement / standards
  • Pain, Intractable / diagnosis
  • Pain, Intractable / etiology
  • Pain, Intractable / surgery
  • Retrospective Studies
  • Spinal Nerve Roots / surgery*
  • Surveys and Questionnaires
  • Young Adult