Beneficial effects of early treatment of nevus of Ota with low-fluence 1,064-nm Q-switched Nd:YAG laser

Dermatol Surg. 2015 Jan;41(1):142-8. doi: 10.1097/DSS.0000000000000212.

Abstract

Background: Childhood nevus of Ota is likely to be more superficial than the adult nevus, therefore early laser treatment of nevus of Ota might have some beneficial effects in children.

Objective: To evaluate the beneficial effects of early treatment of nevus of Ota with a low-fluence 1,064-nm Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) laser.

Materials and methods: The authors performed a retrospective study of 31 Korean patients (Fitzpatrick skin Type IV) with nevus of Ota. The patients received a series of 6 to 32 treatment sessions at 2- to 3-week intervals with a Q-switched Nd:YAG laser at settings of 7- or 8-mm spot, 1.9 to 5.0 J/cm2 mean fluence.

Results: The mean fluence was less in patients younger than 10 years (2.2 ± 0.3 J/cm2) than in those older than 10 years (2.8 ± 0.8 J/cm2) (p = .006). Patients who started their first treatment earlier required fewer treatment sessions to reach moderate, marked, and near total improvement (p < .05). By starting treatment early, low mean fluence was required to reach the end point in each session (p < .001). Post-treatment hyperpigmentation was observed in 1 patient.

Conclusion: This treatment was clinically effective and safe for early nevus of Ota using a low-fluence Q-switched Nd:YAG laser.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Facial Neoplasms / surgery*
  • Female
  • Humans
  • Infant
  • Lasers, Solid-State / adverse effects
  • Lasers, Solid-State / therapeutic use*
  • Male
  • Middle Aged
  • Nevus of Ota / surgery*
  • Retrospective Studies
  • Secondary Prevention
  • Skin Neoplasms / surgery*
  • Time Factors
  • Treatment Outcome
  • Young Adult