In the last decade, peanut oral immunotherapy research has shown promise as an alternative treatment to avoidance in peanut-allergic patients. Research has not only focused on desensitization, but also on immunologic changes and sustained-tolerance. This article reviews the current literature and the historical background of oral immunotherapy as well as immune mechanisms in oral immunotherapy and other therapies being explored in food allergic individuals.
Keywords: DC, dendritic cells; FAHF-2, food allergy herbal formula-2; OFC, oral food challenge; OIT, oral immunotherapy; SCIT, subcutaneous immunotherapy; TCM, traditional Chinese medicine; desensitization; food allergy; iTreg, induced Treg cells; oral immunotherapy; peanut; treatment.