Functional analysis of protective IL1RL1 variants associated with asthma risk

J Allergy Clin Immunol. 2015 Apr;135(4):1080-1083.e3. doi: 10.1016/j.jaci.2014.10.028. Epub 2014 Dec 4.

Authors

Vladimir Ramirez-Carrozzi¹, Amy Dressen², Patrick Lupardus³, Brian Yaspan², Rajita Pappu⁴

Affiliations

¹ Department of Immunology Discovery, Genentech, South San Francisco, Calif.
² Department of Human Genetics, Genentech, South San Francisco, Calif.
³ Department of Structural Biology, Genentech, South San Francisco, Calif.
⁴ Department of Immunology Discovery, Genentech, South San Francisco, Calif. Electronic address: rajitap@gene.com.

PMID: 25483601
DOI: 10.1016/j.jaci.2014.10.028

No abstract available

Publication types

Letter

MeSH terms

Asthma / genetics*
Asthma / metabolism
Genetic Predisposition to Disease
Genetic Variation*
Humans
Interleukin-1 Receptor-Like 1 Protein
Receptors, Cell Surface / chemistry
Receptors, Cell Surface / genetics*
Receptors, Cell Surface / metabolism
Risk

Substances

IL1RL1 protein, human
Interleukin-1 Receptor-Like 1 Protein
Receptors, Cell Surface