Abstract
Three new phenolic compounds (1-3) were isolated from the heartwood of Dalbergia odorifera T. Chen. (Leguminosae). Their structures were established based on spectroscopic methods including 1D and 2D NMR (HSQC, COSY, HMBC and ROESY). Compound 2 exhibited cytotoxicity against BEL-7402 tumor cell lines.
Keywords:
Dalbergia odorifera; cytotoxic activity; leguminosae; phenolic compounds.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification*
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Antineoplastic Agents, Phytogenic / pharmacology
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Benzofurans / chemistry
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Benzofurans / isolation & purification*
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Benzofurans / pharmacology
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Chromones / chemistry
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Chromones / isolation & purification*
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Chromones / pharmacology
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Dalbergia / chemistry*
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Drug Screening Assays, Antitumor
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology
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Flavonoids / chemistry
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Flavonoids / isolation & purification*
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Flavonoids / pharmacology
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Heterocyclic Compounds, 4 or More Rings / chemistry
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Heterocyclic Compounds, 4 or More Rings / isolation & purification*
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Heterocyclic Compounds, 4 or More Rings / pharmacology
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Humans
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Phenols / chemistry
Substances
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2-(4,5-dimethoxy-5-(3-m-hydroxyphenyl-trans-allyl)cyclohexa-3,6-dien-2-on-1-ylmethyl)-5-hydroxy-6-methoxy-3-phenylbenzofuran
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6,7-dimethoxy-2-(4-methoxy-benzoquinonyl)-flavan
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7-hydroxy-5'-methoxyspiro(benzo(d)(1,3)dioxole-2',3-chroman)-4-one
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Antineoplastic Agents, Phytogenic
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Benzofurans
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Chromones
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Drugs, Chinese Herbal
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Flavonoids
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Heterocyclic Compounds, 4 or More Rings
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Phenols