Biotechnological potential of Clostridium butyricum bacteria

Braz J Microbiol. 2014 Oct 9;45(3):892-901. doi: 10.1590/s1517-83822014000300019. eCollection 2014.

Abstract

In response to demand from industry for microorganisms with auspicious biotechnological potential, a worldwide interest has developed in bacteria and fungi isolation. Microorganisms of interesting metabolic properties include non-pathogenic bacteria of the genus Clostridium, particularly C. acetobutylicum, C. butyricum and C. pasteurianum. A well-known property of C. butyricum is their ability to produce butyric acid, as well as effectively convert glycerol to 1,3-propanediol (38.2 g/L). A conversion rate of 0.66 mol 1,3-propanediol/mol of glycerol has been obtained. Results of the studies described in the present paper broaden our knowledge of characteristic features of C. butyricum specific isolates in terms of their phylogenetic affiliation, fermentation capacity and antibacterial properties.

Keywords: 1, 3-propanediol; C. butyricum; Clostridium spp.; glycerol; metabolic activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biotechnology / methods*
  • Biotransformation
  • Butyric Acid / metabolism*
  • Clostridium butyricum / classification
  • Clostridium butyricum / growth & development
  • Clostridium butyricum / isolation & purification
  • Clostridium butyricum / metabolism*
  • Cluster Analysis
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • DNA, Ribosomal / chemistry
  • DNA, Ribosomal / genetics
  • Glycerol / metabolism*
  • Industrial Microbiology*
  • Phylogeny
  • Propylene Glycols / metabolism*
  • RNA, Ribosomal, 16S / genetics
  • Sequence Analysis, DNA

Substances

  • DNA, Bacterial
  • DNA, Ribosomal
  • Propylene Glycols
  • RNA, Ribosomal, 16S
  • Butyric Acid
  • 1,3-propanediol
  • Glycerol