1 1Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand 2Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA 3Department of Oncology and Pathology, Karolinska University Hospital, Solna, Stockholm, Sweden 4Aquesta Pathology and University of Queensland, Brisbane, Qld, Australia 5Trillium Health Partners, Mississauga and McMaster University, Hamilton, ON, Canada 6Department of Pathology, Yale University School of Medicine, New Haven, CT, USA 7Institute for Precision Medicine and the Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell, University and New York-Presbyterian Hospital, New York, NY, USA 8Department of Pathology, Urology and Oncology, Johns Hopkins School of Medicine, Baltimore, MA, USA 9Department of Urology, University of Washington, Seattle, WA, USA 10Department of Surgery, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand 11Division of Urology, Sunnybrook Health Sciences, Centre, University of Toronto, Toronto, ON, Canada 12Department of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, CA, USA 13Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA 14Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA 15Section of Pathological Anatomy, Department of Biomedical Sciences and Public Health, Polytechnic University of the Marche Region (Ancona), Ancona, Italy 16University Health Network, University of Toronto, Toronto, Ontario, Canada 17Pathology and Laboratory Medicine Institute, Cleveland Clinic Foundation, Cleveland, OH, USA 18Department of Cellular Pathology, The Royal London Hospital, London, UK 19Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA 20Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, USA 2