A novel hydrophilic polymer-brush pattern for site-specific capture of blood cells from whole blood

Chem Commun (Camb). 2015 Mar 11;51(20):4200-3. doi: 10.1039/c4cc09096a.

Abstract

A novel hydrophilic PAMPS-PAAm brush pattern is fabricated to selectively capture blood cells from whole blood. PAMPS brushes provide antifouling surfaces to resist protein and cell adhesion while PAAm brushes effectively entrap targeted proteins for site-specific and cell-type dependent capture of blood cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acrylic Resins / chemistry*
  • Erythrocytes / chemistry*
  • Hydrophobic and Hydrophilic Interactions
  • Polyethylenes / chemistry*
  • Polymers / chemistry*
  • Polystyrenes / chemistry*
  • Sulfonic Acids / chemistry*

Substances

  • Acrylic Resins
  • Polyethylenes
  • Polymers
  • Polystyrenes
  • Sulfonic Acids
  • styrene-ethylene-butylene-styrene-block copolymer
  • poly(2-acrylamido-2-methyl-1-propanesulfonic acid)
  • polyacrylamide