[Post-traumatic mucormycosis due to Lichtheimia corymbifera: three case reports]

J Mycol Med. 2014 Dec;24(4):345-50. doi: 10.1016/j.mycmed.2014.10.013. Epub 2014 Nov 20.
[Article in French]

Abstract

We report 3 cases of post-traumatic cutaneous mucormycosis caused by Lichtheimia corymbifera, two of them occurring after a farm working accident. Management of post-traumatic mucormycoses consists of a wide excision of the infected tissue, combined with immediate antifungal therapy. Liposomal amphotericin B is the recommended first line treatment. Few studies have evaluated the efficacy of posaconazole. All 3 patients received a surgical debridement and liposomal amphotericin B, which was followed by posaconazole in 2 cases. The duration of the antifungal treatment is not yet well defined. All three patients received a treatment of five weeks with a favorable outcome.

Keywords: Cutaneous mucormycosis; Lichtheimia corymbifera; Mucormycoses; Mucormycoses cutanées; Mucormycoses post-traumatiques; Mucormycosis; Posaconazole; Post-traumatic mucormycosis.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Absidia / isolation & purification*
  • Adolescent
  • Adult
  • Antifungal Agents / therapeutic use
  • Debridement
  • Dermatomycoses / drug therapy
  • Dermatomycoses / microbiology*
  • Dermatomycoses / surgery
  • Humans
  • Immunocompromised Host
  • Male
  • Middle Aged
  • Mucormycosis / drug therapy
  • Mucormycosis / microbiology*
  • Mucormycosis / surgery
  • Wounds and Injuries / drug therapy
  • Wounds and Injuries / microbiology*
  • Wounds and Injuries / surgery

Substances

  • Antifungal Agents