Larvicidal activity of the methanol extract and fractions of the green fruits of Solanum lycocarpum (Solanaceae) against the vector Culex quinquefasciatus (Diptera: Culicidae)

Rev Soc Bras Med Trop. 2014 Sep-Oct;47(5):646-8. doi: 10.1590/0037-8682-0010-2014.

Abstract

Introduction: The larvicidal activity of Solanum lycocarpum against Culex quinquefasciatus is unknown.

Methods: We evaluated the larvicidal activity of extracts of the green fruits of Solanum lycocarpum against third and fourth instar larvae of C. quinquefasciatus.

Results: Dichloromethane and ethyl acetate fractions showed the greatest larvicidal effect at 200mg/L (83.3% and 86.7%, respectively). The methanol and dichloromethane, ethyl acetate, and hydromethanolic fractions demonstrated larvicidal effects against C. quinquefasciatus, with LC50 values of 126.24, 75.13, 83.15, and 207.05 mg/L, respectively.

Conclusions: Thus, when considering new drugs with larvicidal activity from natural products, S. lycocarpum fruits may be good candidate sources.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biological Assay
  • Culex / drug effects*
  • Larva / drug effects
  • Lethal Dose 50
  • Plant Extracts / pharmacology*
  • Solanum / chemistry*

Substances

  • Plant Extracts