Elevated carcinoembryonic antigen tumour marker caused by head and neck cancer: a case report and literature study

Cancer Radiother. 2015 Apr;19(2):106-10. doi: 10.1016/j.canrad.2014.09.008. Epub 2014 Nov 17.

Abstract

Carcinoembryonic antigen is a tumour marker commonly increased in gastrointestinal and pulmonary cancers. We report a case of a 46-year-old man with a mucoepidermoid carcinoma of the base of tongue with an elevated and traceable serum carcinoembryonic antigen level. This antigen proved to be a valuable marker in the treatment follow-up. When a raised carcinoembryonic antigen level is found, salivary gland malignancies should be taken into the differential diagnosis and clinical examination of the head and neck region should not be overlooked.

Keywords: Antigène carcinoembryonique; CEA; Cancer ORL; Cancer mucoépidermoïde; Head and neck cancer; Minor salivary gland tumours; Mucoepidermoid carcinoma; Tumeur des glandes salivaires.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Articulation Disorders / etiology
  • Barrett Esophagus / diagnosis
  • Biomarkers, Tumor / blood*
  • Carcinoembryonic Antigen / blood*
  • Carcinoma, Mucoepidermoid / blood*
  • Carcinoma, Mucoepidermoid / diagnostic imaging
  • Carcinoma, Mucoepidermoid / radiotherapy
  • Carcinoma, Mucoepidermoid / surgery
  • Combined Modality Therapy
  • Deglutition Disorders / etiology
  • Delayed Diagnosis
  • Follow-Up Studies
  • Gastroesophageal Reflux / diagnosis
  • Gastroesophageal Reflux / drug therapy
  • Humans
  • Male
  • Middle Aged
  • Organ Specificity
  • Proton Pump Inhibitors / therapeutic use
  • Radiotherapy, Adjuvant
  • Remission Induction
  • Salivary Gland Neoplasms / blood*
  • Salivary Gland Neoplasms / diagnostic imaging
  • Salivary Gland Neoplasms / radiotherapy
  • Salivary Gland Neoplasms / surgery
  • Salivary Glands, Minor / pathology
  • Salivary Glands, Minor / surgery
  • Tomography, X-Ray Computed
  • Tongue Neoplasms / blood*
  • Tongue Neoplasms / diagnostic imaging
  • Tongue Neoplasms / radiotherapy
  • Tongue Neoplasms / surgery

Substances

  • Biomarkers, Tumor
  • Carcinoembryonic Antigen
  • Proton Pump Inhibitors