Probiotics use has been researched for gastrointestinal health. The oral cavity, of course, is not a separate component of the body, and because both periodontal disease and dental caries are bacterial diseases, a probiotics approach to treating these maladies is currently being evaluated. Several over-the-counter products claim to be formulated with probiotics and suitable for use for oral care. In this article, the authors define probiotics, review research that explores probiotics in relation to periodontal disease and caries, and identify available probiotics products aimed at promoting oral health.