[Fecal microbiota transplantation]

Gastroenterol Hepatol. 2015 Mar;38(3):123-34. doi: 10.1016/j.gastrohep.2014.07.010. Epub 2014 Nov 18.
[Article in Spanish]

Abstract

Bacteria can no longer be seen as an enemy. Nowadays, there is enough evidence to place the microbiota as a key element in human homeostasis. Despite initial skepticism, fecal microbiota transplantation (FMT) is a real therapeutic alternative for patients with recurrent Clostridium difficile infection. Moreover, this procedure has shown promising results in ulcerative colitis and other non-gastrointestinal disorders. There is still a lack of knowledge and clinical trials with long- term follow-up. Therefore, the available data should be interpreted with caution. In this document we provide a detailed review of the literature on the intestinal microbiota and FMT.

Keywords: Clostridium difficile; Enfermedad inflamatoria intestinal; Fecal microbiota transplantation; Inflammatory bowel disease; Trasplante de microbiota fecal.

MeSH terms

  • Animals
  • Clinical Trials as Topic
  • Clostridioides difficile
  • Enterocolitis, Pseudomembranous / microbiology
  • Enterocolitis, Pseudomembranous / therapy
  • Fecal Microbiota Transplantation* / adverse effects
  • Fecal Microbiota Transplantation* / methods
  • Fecal Microbiota Transplantation* / standards
  • Germ-Free Life
  • Humans
  • Inflammatory Bowel Diseases / microbiology
  • Inflammatory Bowel Diseases / therapy
  • Intestines / immunology
  • Intestines / microbiology
  • Metabolic Syndrome / microbiology
  • Metabolic Syndrome / therapy
  • Microbiota