Solitary fibrous tumor of the liver: report of two cases and review of the literature

Int J Surg. 2014 Dec;12(12):1291-4. doi: 10.1016/j.ijsu.2014.10.037. Epub 2014 Nov 4.

Abstract

A solitary fibrous tumor (SFT) of the liver is a rare neoplasm of mesenchymal origin. 59 cases have been reported in the literature. We report 2 patients who presented with a hepatic solitary fibrous tumor. The first case is a 65-year-old man who presented with an accidental finding of a large mass in the left liver. Biopsy revealed an SFT and left hepatectomy was performed. The diagnosis was confirmed by histopathology. The second case is an 87-year-old woman who presented with disturbances in her liver function tests. A Computed Tomography (CT) scan showed a large mass in the right liver. Surgery was contraindicated because of the patient's poor general condition. A biopsy was done and SFT was diagnosed histopathologically. SFT are usually benign but the risk of malignant transformation always exists, which mandates surgical resection as the optimal management of these tumors. However, because of the small sample size and the rarity of the entity, it is difficult to define the evolution, the risk factors and the malignant potential of these tumors.

Keywords: Histopathology; Liver; MRI; Solitary fibrous tumor; Surgery.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Biopsy
  • Female
  • Humans
  • Incidental Findings
  • Liver / pathology
  • Liver Neoplasms / diagnosis*
  • Liver Neoplasms / epidemiology
  • Liver Neoplasms / pathology
  • Magnetic Resonance Imaging
  • Male
  • Rare Diseases / diagnosis*
  • Rare Diseases / epidemiology
  • Rare Diseases / pathology
  • Solitary Fibrous Tumors / diagnosis*
  • Solitary Fibrous Tumors / epidemiology
  • Solitary Fibrous Tumors / pathology