Isolation and characterization of a novel H10N2 avian influenza virus from a domestic duck in Eastern China

Infect Genet Evol. 2015 Jan:29:1-5. doi: 10.1016/j.meegid.2014.10.029. Epub 2014 Nov 7.

Abstract

During the surveillance for avian influenza viruses (AIVs) in live poultry markets (LPMs) in Eastern China, in 2013, an H10N2 AIV was isolated from a domestic duck. Phylogenetic analysis showed that this strain received its genes from H10, H1 and H7 AIVs of wild birds in China. The virulence of this strain was examined in chickens and mice, and was found to be low pathogenic in chickens but demonstrated moderate pathogenicity in mice. These results suggest that active surveillance of AIVs in LPMs should be used in an early warning system for avian influenza outbreaks.

Keywords: Avian influenza viruses; Domestic ducks; Genetic analysis; H10N2; Reassortment.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Ducks*
  • Environmental Monitoring
  • Influenza A virus / classification*
  • Influenza A virus / genetics
  • Influenza A virus / isolation & purification*
  • Influenza A virus / pathogenicity
  • Influenza in Birds / genetics*
  • Influenza in Birds / virology
  • Mice
  • Orthomyxoviridae Infections / virology
  • Phylogeny
  • Population Surveillance
  • RNA, Viral / genetics

Substances

  • RNA, Viral