Comparison of the reduction in the antibacterial potency of a fluoroquinolone conferred by a single mutation in the quinolone resistance-determining region or by the inoculum size effect

Int J Antimicrob Agents. 2014 Nov;44(5):472-4. doi: 10.1016/j.ijantimicag.2014.07.007. Epub 2014 Aug 23.

Authors

Aude A Ferran¹, Pierre-Louis Toutain², Alain Bousquet-Melou²

Affiliations

¹ INRA, UMR 1331, Toxalim, Research Centre in Food Toxicology, F-31027 Toulouse, France; Université de Toulouse, ENVT, INP, Toxalim, F-31076 Toulouse, France. Electronic address: a.ferran@envt.fr.
² INRA, UMR 1331, Toxalim, Research Centre in Food Toxicology, F-31027 Toulouse, France; Université de Toulouse, ENVT, INP, Toxalim, F-31076 Toulouse, France.

PMID: 25442360
DOI: 10.1016/j.ijantimicag.2014.07.007

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / pharmacology*
Bacteria / drug effects*
Colony Count, Microbial
Fluoroquinolones / pharmacology*
Genetic Loci*
Microbial Sensitivity Tests
Mutation*

Substances

Anti-Bacterial Agents
Fluoroquinolones