The concepts and applications of tissue engineering in otorhinolaryngology

Acta Otorrinolaringol Esp. 2015 Jan-Feb;66(1):43-8. doi: 10.1016/j.otorri.2014.03.007. Epub 2014 Oct 25.
[Article in English, Spanish]

Abstract

Introduction: Tissue engineering is a rapidly developing field that, making biological substitutes for the repair and regeneration of damaged tissues, will play an important role in the future of otorhinolaryngology.

Objective: In this article we explain the principles of regenerative medicine and its potential applications in Otorhinolaryngology.

Materials and methods: The authors searched the published literature on this topic, chose relevant references, and extracted and systematized the data.

Results and conclusion: There are some exciting possibilities for future treatments in otorhinolaryngology applying the concepts of tissue engineering.

Keywords: Cuerdas vocales; Ear pinna; Ingeniería de tejidos; Oreja; Perforación de la membrana timpánica; Rhinoplasty; Rinoplastia; Tissue engineering; Trachea; Tráquea; Tympanic membrane perforation; Vocal cords.

Publication types

  • Review

MeSH terms

  • Cell- and Tissue-Based Therapy / methods
  • Extracellular Matrix / metabolism
  • Forecasting
  • Humans
  • Hyaluronic Acid / therapeutic use
  • Intercellular Signaling Peptides and Proteins / therapeutic use
  • Otolaryngology / methods*
  • Otolaryngology / trends
  • Plastic Surgery Procedures / methods
  • Regenerative Medicine / methods*
  • Regenerative Medicine / trends
  • Stem Cell Transplantation
  • Tissue Engineering*
  • Vasodilator Agents / therapeutic use
  • Vibration
  • Vocal Cords / physiology
  • Vocal Cords / surgery

Substances

  • Intercellular Signaling Peptides and Proteins
  • Vasodilator Agents
  • Hyaluronic Acid