The future of carbon-based scaffolds in foot and ankle surgery

Clin Podiatr Med Surg. 2015 Jan;32(1):73-91. doi: 10.1016/j.cpm.2014.09.001.

Abstract

Carbon may represent an alternative material suitable for future development as a soft-tissue substitute that potentially optimizes the biological and mechanical properties required for a graft product used in surgery. In addition, other modes of characterization such as 3-dimensional computational modeling may offer an insight into material performance in a biological environment. Further investigation is required to characterize and model the relationships between biological, mechanical, and design properties of this material to maximize its potential as a biomechanical scaffold and vehicle for delivering biologics that promote tissue repair and regeneration.

Keywords: Biologics; Biomaterials; Biomechanics; Carbon; Cell growth; Reconstruction; Scaffolds; Tissue.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Carbon*
  • Cell Culture Techniques
  • Elastic Modulus
  • Fibroblasts / physiology
  • Foot / surgery*
  • Guided Tissue Regeneration / instrumentation*
  • Humans
  • Materials Testing
  • Porosity
  • Tensile Strength
  • Tissue Scaffolds*

Substances

  • Carbon