Whole mitochondrial genome sequence of a rat colorectal cancer MCA38 cell line

Chun-Fen Zhang; Xiao-Jie Yu; Bao-Yong Wang; Hong-Wei Chen; Cheng-En Hu

doi:10.3109/19401736.2014.974176

Whole mitochondrial genome sequence of a rat colorectal cancer MCA38 cell line

Mitochondrial DNA A DNA Mapp Seq Anal. 2016 May;27(3):2034-5. doi: 10.3109/19401736.2014.974176. Epub 2014 Dec 1.

Authors

Chun-Fen Zhang¹, Xiao-Jie Yu², Bao-Yong Wang¹, Hong-Wei Chen¹, Cheng-En Hu³

Affiliations

¹ a Department of Gastroenterology , Affiliated Luoyang Central Hospital of Zhengzhou University , Luoyang , P.R. China .
² b College of Animal Science and Technology, Hebei North University , Zhangjiakou , P.R. China , and.
³ c Department of General Surgery , Affiliated Huashan Hospital of Fudan University , Shanghai , P.R. China.

PMID: 25434994
DOI: 10.3109/19401736.2014.974176

Abstract

Colorectal cancer (CRC) is the second most fatal and the third most diagnosed type of cancer worldwide. We sequenced a complete mitochondrial genome sequence of a rat CRC cell line MCA38 for the first time. The total length of the mitogenome was 16,305 bp and coding 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes. This mitochondrial genome sequence will provide new genetic resource into Colon cancer disease.

Keywords: Colorectal cancer; MCA38 cell line; mitochondrial genome.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Base Sequence
Cell Line, Tumor
Colorectal Neoplasms / genetics*
Genes, Mitochondrial
Genome, Mitochondrial*
RNA, Transfer / genetics
Rats

Substances

RNA, Transfer