Comparative characterization of the skull bones after implantation of titanium biocomposites containing BMP-2 in their coating structure

T V Pavlova; L A Pavlova; A V Nesterov; D A Kolesnikov; A I Shchyogolev

doi:10.1007/s10517-014-2739-y

Comparative characterization of the skull bones after implantation of titanium biocomposites containing BMP-2 in their coating structure

Bull Exp Biol Med. 2014 Dec;158(2):274-7. doi: 10.1007/s10517-014-2739-y. Epub 2014 Nov 29.

Authors

T V Pavlova¹, L A Pavlova, A V Nesterov, D A Kolesnikov, A I Shchyogolev

Affiliation

¹ Belgorod State National Research University, Moscow, Russia, lpavlova@bsu.edu.ru.

PMID: 25432287
DOI: 10.1007/s10517-014-2739-y

Abstract

The skull bone tissue was studied under conditions of implantation of Grey nanostructured titanium containing biocomposites and bone morphogenetic protein-2 in the coating structure. Implantation of sandblast processed titanium led to more rapid formation of the bone tissue than the use of titanium biocomposites with microarch oxidation (due to porous surface). The type of metal processing was inessential for nanocomposites. Morphogenetic proteins stimulated regeneration and facilitated the formation of structures characteristic of the bone tissue.

Publication types

Comparative Study

MeSH terms

Animals
Bone Morphogenetic Protein 2 / metabolism*
Bone Regeneration / physiology*
Coated Materials, Biocompatible / chemistry*
Humans
Image Processing, Computer-Assisted
Microscopy, Atomic Force
Nanocomposites / chemistry*
Nanocomposites / therapeutic use
Nanotechnology / methods
Nanotechnology / trends
Rats
Skull / chemistry*
Skull / physiology
Time Factors
Titanium / chemistry*

Substances

BMP2 protein, human
Bone Morphogenetic Protein 2
Coated Materials, Biocompatible
Titanium