Neonatal renal failure: a complication of maternal antihypertensive therapy

Am J Obstet Gynecol. 1989 May;160(5 Pt 1):1223-4. doi: 10.1016/0002-9378(89)90197-x.

Abstract

Persistent anuria was diagnosed in a neonate born to a mother whose pregnancy was complicated by severe hypertension and systemic lupus erythematosus. Severe maternal hypertension necessitated the use of a battery of antihypertensive medications that included enalapril, an angiotensin converting enzyme inhibitor. The role of enalapril in neonatal renal failure is discussed.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / chemically induced*
  • Acute Kidney Injury / pathology
  • Antihypertensive Agents / adverse effects*
  • Anuria / chemically induced
  • Anuria / pathology
  • Drug Therapy, Combination
  • Enalapril / adverse effects
  • Female
  • Humans
  • Hyaline Membrane Disease / pathology
  • Hypertension / drug therapy*
  • Hypertension / etiology
  • Infant, Newborn
  • Kidney / pathology
  • Lupus Erythematosus, Systemic / complications
  • Male
  • Pregnancy
  • Pregnancy Complications / drug therapy*
  • Pregnancy Complications / etiology

Substances

  • Antihypertensive Agents
  • Enalapril