Antioxidant and antifungal activity of different extracts obtained from aerial parts of Inula crithmoides L

Nat Prod Res. 2015;29(12):1173-6. doi: 10.1080/14786419.2014.983102. Epub 2014 Nov 26.

Abstract

The total phenolic content, antioxidant and antifungal activities of three Inula crithmoides extracts (n-hexane, methylene chloride and MeOH) were investigated. The methanolic extract showed the highest total phenolic content. In the DPPH assay, the methanolic and hexane extracts exhibited the highest DPPH-radical scavenging activity; in the 5-lipoxygenase assay, the hexane extract showed greater inhibitory effect with an IC50 similar to that of Trolox and ascorbic acid. The antifungal activity of the methanolic extract revealed a higher activity against Phytophtora cryptogea and Alternaria solani.

Keywords: Inula crithmoides; antifungal activity; antioxidant activity; phenolics.

MeSH terms

  • Alternaria / drug effects
  • Anti-Inflammatory Agents / pharmacology
  • Antifungal Agents / pharmacology*
  • Free Radical Scavengers / pharmacology*
  • Inula / chemistry*
  • Phenols / chemistry*
  • Phytophthora / drug effects
  • Plant Components, Aerial / chemistry
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology*

Substances

  • Anti-Inflammatory Agents
  • Antifungal Agents
  • Free Radical Scavengers
  • Phenols
  • Plant Extracts