Isolation of a new lycodine alkaloid from Lycopodium japonicum

Nat Prod Res. 2015;29(8):735-8. doi: 10.1080/14786419.2014.984184. Epub 2014 Nov 25.

Abstract

A new lycodine alkaloid, N-methylhydroxypropyllycodine (1), was isolated from the club moss Lycopodium japonicum Thunb, together with five known compounds, N-methyllycodine (2), huperzinine (3), β-obscurine (4), α-obscurine (5) and des-N-methyl-α-obscurine (6). Their structures were elucidated by spectroscopic analyses, including 2D NMR techniques.

Keywords: Lycopodiaceae; Lycopodium japonicum; lycodine alkaloid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaloids / chemistry*
  • Alkaloids / isolation & purification
  • Heterocyclic Compounds, 4 or More Rings / chemistry*
  • Heterocyclic Compounds, 4 or More Rings / isolation & purification
  • Lycopodium / chemistry*
  • Molecular Structure

Substances

  • Alkaloids
  • Heterocyclic Compounds, 4 or More Rings
  • N-methylhydroxypropyllycodine
  • obscurine
  • huperzinine
  • lycodine