Recombinant luteinizing hormone supplementation in women undergoing in vitro fertilization/ intracytoplasmic sperm injection with gonadotropin releasing hormone antagonist protocol: a systematic review and meta-analysis

Reprod Biol Endocrinol. 2014 Nov 24:12:109. doi: 10.1186/1477-7827-12-109.

Abstract

The objective of this meta-analysis is to assess the impact of LH supplementation in women undergoing in vitro fertilization/ intracytoplasmic sperm injection (IVF/ICSI) with gonadotropin releasing hormone (GnRH) antagonist protocol. No significant difference in outcomes between LH supplementation and r-FSH alone in women undergoing IVF/ICSI with GnRH antagonist protocol is currently present, and further studies are necessary for more solid conclusions on pregnancy likelihood to be drawn.

Publication types

  • Meta-Analysis
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Dietary Supplements
  • Female
  • Fertilization in Vitro*
  • Gonadotropin-Releasing Hormone / antagonists & inhibitors*
  • Humans
  • Luteinizing Hormone / administration & dosage*
  • Luteinizing Hormone / genetics
  • Pregnancy
  • Pregnancy Outcome
  • Recombinant Proteins / administration & dosage
  • Sperm Injections, Intracytoplasmic*
  • Systematic Reviews as Topic

Substances

  • Recombinant Proteins
  • Gonadotropin-Releasing Hormone
  • Luteinizing Hormone