Carbon-CArbon bond formation by Lewis superacid catalysis

Chem Biodivers. 2014 Nov;11(11):1752-63. doi: 10.1002/cbdv.201400020.

Abstract

Diverse intramolecular cyclizations involving the formation of CC bonds are described using catalytic methodologies based on Lewis superacids. Examples are presented on 1,6-diene cyclizations to gem-dimethylcyclohexane structures. Tandem cyclization of trienes are described to afford bicyclic structures in reactions involving rearrangements. Hydroarylation of olefins and of allenes is developed in catalytic FriedelCrafts-type coupling processes, which can give rise to tandem reactions. The olfactory evaluation of the series of prepared compounds is also presented.

Keywords: Cyclization reactions; CC Bond formation; Lewis superacids; Olefin functionalization; Olfactory evaluation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alkadienes / chemistry*
  • Carbon / chemistry*
  • Catalysis
  • Cyclization
  • Cyclohexanes / chemical synthesis*
  • Cyclohexanes / chemistry
  • Lewis Acids / chemistry*
  • Molecular Structure

Substances

  • Alkadienes
  • Cyclohexanes
  • Lewis Acids
  • Carbon