Abstract
This review provides an overview of latest insights in epithelial ovarian cancer biology. The current understanding of the origin and the complex heterogeneity are depicted, followed by an introduction to the latest therapeutic approaches. The role of the tumor microenvironment, the high potential to disseminate within the peritoneal cavity, and new molecular biological findings are summarized.
MeSH terms
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Antineoplastic Agents / therapeutic use
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Carcinoma / physiopathology*
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Carcinoma / secondary
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Carcinoma / therapy
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Combined Modality Therapy
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Disease Progression
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Female
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Humans
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Molecular Targeted Therapy
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Ovarian Neoplasms / physiopathology*
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Ovarian Neoplasms / therapy
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Ovariectomy
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Palliative Care
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Peritoneal Neoplasms / physiopathology
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Peritoneal Neoplasms / secondary
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Peritoneal Neoplasms / therapy
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Prognosis
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Tumor Microenvironment / physiology