Fundus autofluorescence in retinopathy caused by deferoxamine toxicity

Retin Cases Brief Rep. 2007 Summer;1(3):120-2. doi: 10.1097/01.ICB.0000279640.76453.eb.

Abstract

Purpose: To describe the fundus autofluorescence photographic pattern in a case of deferoxamine retinopathy.

Methods: Observational case report.

Results: A 91-year-old woman receiving intravenous deferoxamine treatment presented with a history of deteriorating vision in both eyes. Autofluorescence photography revealed well circumscribed areas of hyperautofluorescence that correlated with areas of pigmentation shown by color photography. Deferoxamine retinopathy was diagnosed.

Conclusion: Fundus autofluorescence photography is a noninvasive imaging method for early detection of deferoxamine retinopathy and can be used to monitor the status of the macula in patients at risk for this toxicity.