Purpose: To report a case of methicillin-resistant Staphylococcus aureus infectious scleritis after vitrectomy for endophthalmitis.
Methods: Retrospective chart review of one patient referred to a tertiary academic center for management of methicillin-resistant S. aureus infectious scleritis. Antecedent history, clinical course, response to treatment, and final visual acuity were documented.
Results: Methicillin-resistant S. aureus infectious scleritis required combination systemic, periocular, intraocular, and topical antibiotics for complete resolution. Visual recovery was limited.
Conclusion: Methicillin-resistant S. aureus infectious scleritis can complicate vitrectomy for endophthalmitis and requires long-term and multiple-route administration of antibiotics for resolution. Greater awareness of this serious complication along with preventive measures may reduce future occurrences.