Monitoring of WT1 and its target gene IRF8 expression in acute myeloid leukemia and their significance

Int J Lab Hematol. 2015 Aug;37(4):e67-71. doi: 10.1111/ijlh.12309. Epub 2014 Nov 11.

Authors

Q Zhang¹, Q Zhang¹, Q Li¹, B Liu¹, Y Wang, D Lin¹, C Zhou¹, W Li¹, K Tang¹, Z Tian¹, M Wang¹, J Wang¹, Y Mi²

Affiliations

¹ State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
² State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China. miyingch@medmail.com.cn.

PMID: 25387409
DOI: 10.1111/ijlh.12309

No abstract available

Publication types

Letter

MeSH terms

Aged
Antineoplastic Agents / therapeutic use
Biomarkers, Tumor / genetics*
Biomarkers, Tumor / metabolism
Bone Marrow / drug effects
Bone Marrow / metabolism
Bone Marrow / pathology
Case-Control Studies
Female
Gene Expression Regulation, Leukemic*
Humans
Induction Chemotherapy
Interferon Regulatory Factors / genetics*
Interferon Regulatory Factors / metabolism
Leukemia, Myeloid, Acute / drug therapy
Leukemia, Myeloid, Acute / genetics*
Leukemia, Myeloid, Acute / mortality
Leukemia, Myeloid, Acute / pathology
Male
Middle Aged
Neoplasm, Residual
Prognosis
Promoter Regions, Genetic
Protein Binding
Remission Induction
Signal Transduction
Survival Analysis
Translocation, Genetic
WT1 Proteins / genetics*
WT1 Proteins / metabolism

Substances

Antineoplastic Agents
Biomarkers, Tumor
Interferon Regulatory Factors
WT1 Proteins
WT1 protein, human
interferon regulatory factor-8