Vasopressin in cirrhosis and sepsis: physiology and clinical implications

G Wagener; J Bakker

Vasopressin in cirrhosis and sepsis: physiology and clinical implications

Minerva Anestesiol. 2015 Dec;81(12):1377-83. Epub 2014 Nov 11.

Authors

G Wagener¹, J Bakker

Affiliation

¹ Department of Anesthesiology, College of Physicians and Surgeons of Columbia University New York, New York, NY, USA - gw72@cumc.columbia.edu.

PMID: 25384691

Abstract

Arginine-vasopressin (AVP) is an important hormone in the regulation of plasma osmolality and blood volume/pressure. In clinical practice it is frequently used in the treatment of septic shock and decompensated cirrhosis. In this review the physiology of AVP and its analogues is presented. In addition the use of AVP in cirrhosis and sepsis is reviewed.

Publication types

Review

MeSH terms

Arginine Vasopressin / physiology
Arginine Vasopressin / therapeutic use
Humans
Liver Circulation / drug effects
Liver Cirrhosis / drug therapy*
Sepsis / drug therapy*
Shock, Septic / drug therapy
Vasoconstrictor Agents / therapeutic use*
Vasopressins / physiology*
Vasopressins / therapeutic use*

Substances

Vasoconstrictor Agents
Vasopressins
Arginine Vasopressin