Supramolecular assemblies of novel aminonucleoside phospholipids and their bonding to nucleic acids

Chem Commun (Camb). 2015 Jan 11;51(3):469-72. doi: 10.1039/c4cc07538b.

Abstract

A novel class of aminonucleoside phospholipids has been developed. These molecules could spontaneously assemble into supramolecular structures including multilamellar organization, hydrogels, superhelical strands, and vesicles. Their ability to bind to DNA by hydrogen bonding and π-π stacking interactions was investigated by many means.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Circular Dichroism
  • Hydrogen Bonding
  • Microscopy, Electron, Scanning
  • Molecular Structure
  • Nucleic Acids / chemistry
  • Nucleic Acids / metabolism*
  • Phospholipids / chemical synthesis*
  • Phospholipids / chemistry
  • Puromycin Aminonucleoside / chemistry*

Substances

  • Nucleic Acids
  • Phospholipids
  • Puromycin Aminonucleoside