Real-time ultrasound elastography for the differentiation of malignant and benign masses in the head and neck

J Craniofac Surg. 2014 Nov;25(6):1971-4. doi: 10.1097/SCS.0000000000001009.

Abstract

Objectives: The objective of this study was to evaluate head and neck masses with real-time elastography to differentiate malignant masses.

Materials and methods: Between January 2011 and December 2012, a total of 51 patients with a palpable mass in the neck region were included in this study. Excisional histopathologic data were compared with elastographic results and Doppler ultrasonography.

Results: The study group comprised 27 males (52.9%) and 24 females (47.1%) (mean [SD] age, 41.47 [19.59] y; range, 4-80 y). Fourteen masses were malignant (27.5%) and 37 were benign (72.5%). Comparing the elastographic results of benign and malignant masses, elastographic scores of the malignant masses were significantly higher than those of the benign masses (P < 0.005).The elastographic scores were divided into 2 groups: 34 (91.9%) patients with the diagnosis of benign mass had the score of 1 to 2, whereas 9 (64.3%) patients with the diagnosis of malignant cases had the score of 3 to 4. There was a significant difference between the groups (P < 0.005).However, 2 squamous cell carcinomas (28.6%) and 1 lymphoma (8.1%) were diagnosed with an elastographic score of 1 (Table 2). This showed that even an elastographic score of 1 was not enough to issue a diagnosis of benign masses.

Conclusions: With improvements in the device and increased experience, this modality can become a useful tool for the routine use. However, this modality cannot be used for screening to merely provide additional information about the nature of the masses.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy / methods
  • Carcinoma, Squamous Cell / diagnostic imaging
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Elasticity Imaging Techniques / methods*
  • Endoscopy / methods
  • Female
  • Head and Neck Neoplasms / diagnostic imaging*
  • Head and Neck Neoplasms / pathology
  • Humans
  • Laryngoscopy
  • Lymphoma / diagnostic imaging
  • Male
  • Middle Aged
  • Prospective Studies
  • Salivary Gland Neoplasms / diagnostic imaging
  • Ultrasonography, Doppler
  • Young Adult