In order to promote preclinical and clinical applications of photoacoustic imaging, novel photoacoustic contrast agents are highly desired for molecular imaging of diseases, especially for deep tumor imaging. Here, perylene-3,4,9,10-tetracarboxylic diiimide-based near-infrared-absorptive organic nanoparticles are reported as an efficient agent for photoacoustic imaging of deep brain tumors in living mice with enhanced permeability and retention effect.
Keywords: Perylene-3,4,9,10-tetracarboxylic diimide nanoparticles; brain tumor; deep tumor imaging; near-infrared-absorption; photoacoustic imaging.
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