Treatment results in the different surgery of intradural extramedullary tumor of 122 cases

PLoS One. 2014 Nov 5;9(11):e111495. doi: 10.1371/journal.pone.0111495. eCollection 2014.

Abstract

Study design: A retrospective study of intradural extramedullary tumor.

Objective: To compare the treatment results in the different surgeries of spinal intradural extramedullary tumor.

Methods: The study retrospectively reviewed 122 patients. The minimally invasive surgery (MIS) group was divided into Group A (hemilaminectomy + tumor microscopic excision) and Group B (laminectomy + tumor microscopic excision + pedicle screw fixation). Meanwhile, the non-MIS group was divided into Group C (hemilaminectomy + tumor excision), Group D (laminectomy + tumor excision), and Group E (laminectomy + tumor excision + pedicle screw fixation). In order to study postoperative spinal stability, we simultaneously divided all of the subjects into three categories, namely Group HE: hemilaminectomy + tumor excision; Group LE: laminectomy + tumor excision; and Group LEPSF: laminectomy + tumor excision + pedicle screw fixation.

Results: The MIS group exhibited fewer postoperative complications (p<0.05), better short-term clinical efficacy (p<0.05) and less non-surgical cost (p<0.05) than in non-MIS group. The rate of postoperative spinal instability in hemilaminectomy was lower than in laminectomy in a single spinal segment (p<0.05). The rate of postoperative spinal instability in laminectomy + pedicle screw fixation was lower than in hemilaminectomy and laminectomy in two or more spinal segments (p<0.05).

Conclusion: In the case of appropriate surgical indications, minimally invasive surgery for intradural extramedullary tumor is a useful method that can successfully produce good clinical results and reduce non-surgical cost. In addition, pedicle screw fixation helps avoid spinal postoperative instability.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Follow-Up Studies
  • Humans
  • Length of Stay
  • Male
  • Middle Aged
  • Minimally Invasive Surgical Procedures / adverse effects
  • Minimally Invasive Surgical Procedures / methods
  • Postoperative Complications
  • Retrospective Studies
  • Spinal Cord Neoplasms / diagnosis
  • Spinal Cord Neoplasms / surgery*
  • Treatment Outcome
  • Young Adult

Grants and funding

The authors acknowledge support from the Guangxi Science and Technology Plan Fund, Gui Ke Gong 1298003-5-1. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.