Facile synthesis of hydrophilic multi-colour and upconversion photoluminescent mesoporous carbon nanoparticles for bioapplications

Qinglu Kong; Lingxia Zhang; Jianan Liu; Meiying Wu; Yu Chen; Jingwei Feng; Jianlin Shi

doi:10.1039/c4cc07121b

Facile synthesis of hydrophilic multi-colour and upconversion photoluminescent mesoporous carbon nanoparticles for bioapplications

Chem Commun (Camb). 2014 Dec 25;50(99):15772-5. doi: 10.1039/c4cc07121b. Epub 2014 Nov 5.

Authors

Qinglu Kong¹, Lingxia Zhang, Jianan Liu, Meiying Wu, Yu Chen, Jingwei Feng, Jianlin Shi

Affiliation

¹ State Key Laboratory of High Performance Ceramic and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P. R. China. zhlingxia@mail.sic.ac.cn jlshi@mail.sic.ac.cn.

PMID: 25371274
DOI: 10.1039/c4cc07121b

Abstract

Hydrophilic mesoporous carbon nanoparticles (MCNs) have been synthesized via an extremely facile precursor carbonization-in-hot solvent route. The synthesized MCNs show well-defined particle and pore size distribution at around 100 nm and 2.7 nm, respectively, and multicolor and upconversion photoluminescence, which endow the MCNs with multicolor/upconversion bioimaging and drug delivery properties.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antibiotics, Antineoplastic / chemistry
Antibiotics, Antineoplastic / toxicity
Carbon / chemistry*
Cell Survival / drug effects
Color
Doxorubicin / chemistry
Doxorubicin / toxicity
Drug Carriers / chemistry
HeLa Cells
Humans
Hydrophobic and Hydrophilic Interactions
Microscopy, Confocal
Nanoparticles / chemistry*
Particle Size
Porosity
Solvents / chemistry
Spectrometry, Fluorescence

Substances

Antibiotics, Antineoplastic
Drug Carriers
Solvents
Carbon
Doxorubicin